Physikalisches Seminar (Biophysik): Potenzielle Bachelorarbeitsthemen – Übersicht

Biophysikseminar (Physikalisches Seminar Biophysik) 3 ECTS-Punkte

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Seminarthemen    ^{_{(wurden im November vergeben und werden am 23 Januar von den Teilnehmern im Seminar vorgetragen)}}

 AG Veigel:

Literatur:
1. Lights action: optical tweezers, Justin Molloy and Miles Padgett, Contemporary Physics 43, 241-258 (2002)
2. Movement and force produced by a single myosin head, Molloy et al. Nature 378, 209-212 (1995)
3. Load-dependent kinetics of force production by smooth muscle myosin... , Veigel et al. Nature Cell Biology 5, 980-986 (2003)
4. Optical manipulation: a step change for biomedical science, Campugan et al. Contemporary Physics 61, 277-294 (2020)

"Regulation of motor proteins"                                                                      (Linus Seifert)

Literatur:

1. Force and velocity measured for single kinesin molecules, Karel Svoboda and Steve Block, Cell 77, 773-784 (1994)

2. Mechanics of the kinesin step, Nicolas Carter and Robert Cross, Nature 435, 308-312 (2005)

3. The gaited gate of the molecular motor, myosin-V, Veigel et al, Nature Cell Biology 4, 59-65 (2002)
4. Application of optical tweezers in cardiovascular research, Yang et al. Frontiers in Bioengineering and Biotec. 10, 947918 (2022)
5. Myosin II adjusts motility properties and... , Al Azzam et al.Cellular and Molecular Bioengineering 15, 451-465 (2022)

AG Braun:

"präbiotische Phosphorilierung und Polymerisation"                                 (Vortragende*r)

Literatur:
1. Thema: Salditt, A., Karr, L., Salibi, E., Le Vay, K., Braun, D., & Mutschler, H. (2023). Ribozyme-mediated RNA synthesis and replication in a model Hadean microenvironment. Nature Communications, 14(1), 1495.
https://www.nature.com/articles/s41467-023-37206-4

"     particle tracking    "                                                                             (Thomas Habedank)
Literatur:

"Emergence of RNA from dew - dry cycles and feeding from solid states" (Vortragende*r)

Literatur:
Calaça Serrão A et al. High-Fidelity Templated Ligation of RNA via 2′,3′-cyclic Phosphate. ChemRxiv. (2023 This content is a preprint and has not been peer-reviewed) https://chemrxiv.org/engage/chemrxiv/article-details/64a301fbba3e99daef744b88
Dass, A. V. et al. (2023). "RNA Oligomerisation without Added Catalyst..". ChemSystemsChem, 5(1), e202200026. https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/syst.202200026

 AG Serwane:

 "Mechanical characterization of developing tissues using ferrofluid droplets" (Yue Ma)

Literatur:
https://www.nature.com/articles/nmeth.4101

 AG Schwille:

 "Image correlation techniques to characterize molecular binding kinetics" (Vortragende*r)

Literatur:
Blumhardt, Mücksch et al. Nano Lett 2018 (siFCS)
https://pubs.acs.org/doi/10.1021/acs.nanolett.8b00875
Stein, Stehr et al. Nano Lett 2019 (lbFCS)
https://pubs.acs.org/doi/10.1021/acs.nanolett.9b03546
Wiseman CSH Protocols 2015 (Überblick über ICS-Techniken Stand 2015)
http://www.cshprotocols.org/lookup/doi/10.1101/pdb.top086124

 AG Liedl:

 "DNA origami crystals as nano-lasers"                                                    (Vortragende*r)

Literatur:                            

Literatur:                                                                                                            

AG Heuer-Jungemann:

 "Functional properties of DNA origami crystals"                                    (Simon Strunz)

Literatur:

 "Nanopore technology (with focus on DNA origami nanopores)"        (Joachim Weidner)

Literatur:

 AG Nickels:

 "Squeezing biomolecules in a Langmuir trough"                                   (Vortragende*r)

Literatur: https://pubs.acs.org/doi/epdf/10.1021/acs.chemrev.1c00754

 AG Lamb:

 "Multi-color FRET"                                                                                   (Vortragende*r)

Literatur:
Wanninger et al. 2023. Deep-Learning Assisted, Single-molecule Imaging analysis (Deep-LASI) of multi-color DNA Origami structures. bioRxiv:2023.2001.2031.526220.
Barth et al. 2019. Quantitative Single-Molecule Three-Color Forster Resonance Energy Transfer by Photon Distribution Analysis. J Phys Chem B

"2-color Orbital Tracking"                                                                       (Leonard Meurer)

Literatur:
Mieskes et al. 2023. Multicolor 3D Orbital Tracking. Small:e2204726.
Wehnekamp et al. 2019. Nanoresolution real-time 3D orbital tracking for studying mitochondrial trafficking in vertebrate axons in vivo. eLife 8

 AG Tinnefeld:

"Superresolution Microscopy with 'local DNA PAINT' ”                          (Xenofon Liaskos)

Literatur:

“Using the distance dependence of fluorescence energy transfer to graphene for single-molecule biophysics”              (Gabriela Zytkiewicz)

Literatur:

Angemeldet:                                   
(Heidtmann, Landgrebe, Rothmaier, Haizmann, Fastabend, Heberger, Herrmann, Pittorru, Krauß, Alali)

(bei Fragen: Mail an Martin Benoit)