Inhaltsbereich
Biophysics of Molecules – Vorlesung
All information and material regarding this lecture can be found on the proper Moodle page:
https://moodle.lmu.de/course/view.php?id=24324
Key for registration:
Protein Structure, Function and Folding
Mo 17.10.22 Introduction (V01)
Di 18.10.22 Proteins, polypeptides, peptide bond
(V02)
properties of amino acids, Ramachandra plot
Mo 24.10.22 Physical interactions of macromolecules (V03)
VdW, electrostatics, hydrogenbonds
Di 25.10.22 Protein folding - hydrophobic collapse (V04)
hydrophobic interaction, Afinsen hypothesis
Mo 31.10.22 Protein folding (V05)
Di 01.11.22 Feiertag, vorlesungsfrei
DNA & RNA
Mo 07.11.22 DNA structure and function (V06)
double helix, base pairing, genetic code, helix-coil transition
Di 08.11.22 RNA structure and function (V07)
translation, secondary structure, ribozymes
Polymer Physics & Single Molecule Mechanics
Mo 14.11.22 Introduction to polymer physics (V08)
force-extension relation, Gaussian chain, semi-flexible chain
Di 15.11.22 Single Molecule Force Spectroscopy (V09)
AFM, force spectroscopy, biotin-streptavidin, Titin, ...
Mo 21.11.22 Torque spectroscopy & DNA mechanics (V10)
magnetic tweezers
Di 22.11.22 Nanopores (V11)
Filaments & Motors
Mo 28.11.22 Cytoskeleton filaments and Actin polymerization (V12)
Di 29.11.22 Polymerization force, thermal ratchet, treatmilling (V13)
Mo 05.12.22 ATP Hydrolysis, Enzymes (Michaelis Menton Kinetics) (V14)
Di 06.12.22 Molecular Motors (introduction and theory) (V15)
Muscle mechanics
Mo 12.12.22 Molecular Motors (cytoskeleton transport) (V16)
Di 13.12.22 Rotary Motors (V17)
viral packaging, ATP-Synthase
Complex Macromolecular Solutions
Mo 19.12.22 Life at low Reynolds Numbers I (V18)
Di 20.12.22 Life at low Reynolds Numbers II (V19)
02.01.22 und 03.01.22: vorlesungsfrei
Mo 09.01.23 Crowding (V12)
Di 10.01.23
Mo 16.01.22
Di 17.01.22
Mo 23.01.22
Di 24.01.22
Mo 30.01.22 KLAUSUR
Di 31.01.22 DNA Nanotechnology
Mo 06.02.22 Nanoagents
Di 07.02.22 Engineering Life