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Biophysics of Molecules – Vorlesung

All information and material regarding this lecture can be found on the proper Moodle page:
https://moodle.lmu.de/course/view.php?id=24324
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Protein Structure, Function and Folding

Mo 17.10.22  Introduction  (V01)

Di 18.10.22   Proteins, polypeptides, peptide bond
 (V02)
                     properties of amino acids, Ramachandra plot

Mo 24.10.22  Physical interactions of macromolecules (V03)
                     VdW, electrostatics, hydrogenbonds

Di 25.10.22   Protein folding - hydrophobic collapse (V04)
                     hydrophobic interaction, Afinsen hypothesis

Mo 31.10.22  Protein folding (V05)

Di 01.11.22  Feiertag, vorlesungsfrei

DNA & RNA

Mo 07.11.22  DNA structure and function (V06)
double helix, base pairing, genetic code, helix-coil transition 

Di 08.11.22  RNA structure and function (V07) 
translation, secondary structure, ribozymes

Polymer Physics & Single Molecule Mechanics

Mo 14.11.22 Introduction to polymer physics (V08)
force-extension relation, Gaussian chain, semi-flexible chain

Di 15.11.22 Single Molecule Force Spectroscopy (V09)
AFM, force spectroscopy, biotin-streptavidin, Titin, ...

Mo 21.11.22 Torque spectroscopy & DNA mechanics (V10)
magnetic tweezers

Di 22.11.22 Nanopores (V11)

Filaments & Motors

Mo 28.11.22 Cytoskeleton filaments and Actin polymerization (V12)

Di 29.11.22 Polymerization force, thermal ratchet, treatmilling (V13)

Mo 05.12.22 ATP Hydrolysis, Enzymes (Michaelis Menton Kinetics) (V14)

Di 06.12.22 Molecular Motors (introduction and theory) (V15)
Muscle mechanics

Mo 12.12.22 Molecular Motors (cytoskeleton transport) (V16)

Di 13.12.22 Rotary Motors (V17)
viral packaging, ATP-Synthase

Complex Macromolecular Solutions

Mo 19.12.22 Life at low Reynolds Numbers I  (V18)

Di 20.12.22 Life at low Reynolds Numbers II  (V19)

02.01.22 und 03.01.22: vorlesungsfrei

Mo 09.01.23 Crowding (V12)

Di 10.01.23

Mo 16.01.22

Di 17.01.22

Mo 23.01.22

Di 24.01.22

Mo 30.01.22   KLAUSUR

Di 31.01.22 DNA Nanotechnology

Mo 06.02.22 Nanoagents

Di 07.02.22 Engineering Life