Physics of Membranes and mRNA Lipid Nanoparticles – Seminar-Schedule

SCHEDULE: Physics of Membranes and mRNA Lipid Nanoparticles

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19.10.21 Lecture Introduction & presentation of seminar topics
               reading: R.Philipps intro (pdf)

26.10.21 Lecture Molecular properties of Water, Oil and Lipids, Lipid self-assembly, 
chemistry of lipids, solubility, hydrophobic effect, lipid self-assembly, critical micelle concentration

02.11.21 Lecture Lyotropic phases, packing parameter, SAXS, chain dynamics, permeability, diffusion, Membrane elasticity, Curvature, bending modulus, bending energy, vesicle shapes, cubic vs lamellar phases, adhesion, fluctuations, steric interaction, supported membranes

09.11.21 Lecture Lipid mixtures and phase separation, Cholesterol and Lipid rafts, Membranes Electrostatics 
Debey Hückel Theory, charge regulated protein lipid interactions

16.11.21 Seminar

23.11.21 Seminar 

30.11.21 Seminar

07.12.21 Seminar

14.12.21 Seminar

21.12.21 no seminar

Christmas BREAK

11.01.22 Lecture Cationic lipids and gene delivery
read and discuss "Structure and Delivery Mechanisms of Cationic lipid–DNA complexes"
reviews: Ewert et al Expert Opin. Biol. Ther. (2005) 5(1) (pdf), Ewert et al Top Curr Chem (2010) 296: 191–226 (pdf) 

18.01.22 Seminar

25.01.22 Seminar

01.02.22 Seminar

08.02.22 no seminar