Protein dynamics across timescales

Proteins are the molecular makers in our body. Researchers successfully identified a vast proteome, a dense web of metabolic interactions, and thousands of static 3D structures. But the essential molecular dynamics causing protein function are still challenging to detect - yet they are our key to understanding the energetics of protein systems.

I will present our results from optical and electrical single-molecule experiments. FRET allows us to watch single proteins at work in real time. And with the NEOtrap, we developed a new label-free technique to monitor single native proteins electrically, using nanopores. Our goal is to push beyond current detection limits to learn how protein function arises at the nanoscale.

The Colloquium will take place online: Zoom (Password: Kolloquium)